The true all‑in cost of Mounjaro and Wegovy over 12 months

Why the starter price misleads

Almost every provider advertises their GLP-1 service with a "from" price. For Mounjaro that's typically somewhere between £149 and £214 per month. For Wegovy, £89 to £150. These prices are real — but they represent only the first month of treatment, on the lowest dose you'll ever take.

The starter dose exists purely to let your body adjust. You don't lose meaningful weight on it. You don't stay on it. Within four weeks, your prescriber will move you up. And up again. And again — until you find the dose that works for you, where you'll stay for the rest of your treatment.

This isn't a conspiracy. Providers aren't hiding anything. But it means the question "how much does this cost?" requires a different answer than "from £X a month" — and almost nobody gives it.

So we calculated it. Using the standard titration schedule for both drugs, live prices from all ten major UK providers, and a worked example that shows exactly what you'd pay each month. Here's the real number.

How the titration schedule works

Both Mounjaro and Wegovy follow a step-up schedule where you increase your dose every four weeks. This is a safety requirement — increasing too quickly significantly raises the risk of side effects.

The dose you end up maintaining on is individual — some people stay at 7.5mg Mounjaro or 1.7mg Wegovy because it works well for them at that level. Others need the maximum dose to achieve adequate appetite suppression. For our calculations, we've modelled two common scenarios for each drug.

Mounjaro titration

Wegovy titration

Mounjaro: what 12 months actually costs

These figures use the standard titration to 10mg maintenance — the most common scenario for patients who achieve good results before the maximum dose. All prices include applicable first-order discounts and delivery charges. Prices verified March 2026.

The spread between cheapest and most expensive is £858 over 12 months — for identical medication, manufactured by the same company, dispensed under the same MHRA licensing. The difference is entirely in what each provider charges for delivering it and servicing the prescription.

Wegovy: what 12 months actually costs

Wegovy is cheaper than Mounjaro at every equivalent stage of treatment — a gap that widened after Eli Lilly's September 2025 wholesale price increase. If you're deciding between the two drugs and cost is a significant factor, Wegovy's lower 12-month total is worth weighing against the clinical evidence for Mounjaro's marginally greater average weight loss.

The cheapest Wegovy over 12 months (£2,009) is over £1,000 less than the cheapest Mounjaro (£3,050). That's a meaningful difference on any budget.

Worked examples: two providers, month by month

To make the difference concrete: here are two providers side by side, showing exactly what you'd pay each month on Mounjaro, titrating to 10mg maintenance.

The EverydayMeds EDM25 code applies to every order, not just the first. That's what makes it structurally different from most promos — the saving compounds over the full year. Over 12 months it saves £300 vs their standard price, and puts them £320 cheaper than Asda over the same period.

Mounjaro vs Wegovy: the cost gap

Choosing between Mounjaro and Wegovy is primarily a clinical decision — your prescriber should guide it based on your health history, any contraindications, and your goals. But cost is legitimately part of that picture, and the numbers are significant enough to mention.

To put that in perspective: choosing Asda Wegovy over Asda Mounjaro saves you £1,080 over 12 months — enough for three months of free treatment, or a meaningful portion of a gym membership, a nutritionist, or whatever your lifestyle support of choice looks like.

Mounjaro does produce marginally better average weight loss in clinical trials — around 22.5% body weight at 15mg vs 20.7% for Wegovy 7.2mg at the new highest dose. Whether that difference justifies £1,000+ more per year is a personal calculation, and one worth making explicitly rather than by default.

Hidden costs nobody mentions

The price tables above capture medication and delivery. They don't capture everything you'll actually spend. A few things to budget for:

Sharps disposal. Most providers include a sharps bin with your first order. When it's full, you'll need to arrange collection through your local council — this is usually free, but requires booking in advance. Some areas charge a small fee.

Side effect management. The first few months involve nausea for many patients, particularly during dose increases. Anti-nausea medication (ondansetron, domperidone) isn't expensive but it adds up. Voy includes side effect medication with your first order as standard — most providers don't.

Weight loss support. The clinical evidence is clear that GLP-1 medications work best alongside meaningful lifestyle changes. If you're starting from scratch with diet or exercise, there may be costs associated with building those habits — a nutritionist consultation, a gym membership, a meal-planning service. None of this is mandatory, but it's worth budgeting for if you want to make the most of the window the medication creates.

What happens when you stop. Most clinical studies show significant weight regain after stopping GLP-1 treatment. Some patients continue indefinitely at a maintenance dose — which means the 12-month cost isn't really a one-off. Others plan an exit with robust lifestyle change in place. Either approach is valid, but "what does year two cost?" is a question worth asking before you start year one.

How to reduce your annual spend

These are the levers that actually move the number, in rough order of impact:

Choose the right provider for your dose. Provider pricing doesn't scale uniformly. At 2.5mg, Asda is cheapest for Mounjaro. At 10mg maintenance, EverydayMeds is cheapest by a significant margin. Run the comparison at your expected maintenance dose, not the starter.

Use new-patient discounts strategically. Most first-order discounts are one-time. EverydayMeds' EDM30 gives £30 off your first order — making month one meaningfully cheaper. After that, you're paying the standard ongoing price, so factor this in when comparing against providers with lower headline rates.

Use longer-plan discounts on Voy. If you're committed to Voy's support model, their 6-month Mounjaro plan saves £20 per month vs the monthly price — reducing their 12-month total from £3,668 to £3,188. Still not cheapest, but closes the gap substantially.

Consider whether you need to titrate to the maximum dose. Many patients achieve their goals at 7.5mg or 10mg Mounjaro. Every dose step up adds to your monthly bill. If your prescriber confirms you're making good progress, staying at a comfortable dose rather than pushing to the maximum is a legitimate cost-saving strategy.

Switch providers once you've found your maintenance dose. Transfer patient discounts are available at Lloyds (START30, £30 off), Boots (WELCOME10, 10% off) and others. The cheapest first-month deal at your maintenance dose, combined with competitive repeat pricing, can beat staying with your original provider.

Common questions

Does everyone need to reach the maximum dose? ▾

No. A significant proportion of patients find their effective maintenance dose below the maximum. For Mounjaro, Voy's clinical data suggests many patients maintain well on 7.5mg or 10mg. For Wegovy, some patients stay on 1.7mg long-term. Your prescriber will help you find the dose that works for you, and staying on a lower dose is both clinically valid and cheaper.

Is it possible to get Mounjaro or Wegovy on the NHS? ▾

Mounjaro became available from some GPs on the NHS from June 2025, but with very strict criteria — BMI over 40 plus four weight-related health conditions. Wegovy is available through NHS specialist weight management services but requires a referral and has long waiting lists in most areas. The majority of people accessing GLP-1 treatment in the UK currently do so privately, which is what all prices in this article reflect.

Can I get support with the cost if I'm on benefits? ▾

Bolt Pharmacy explicitly offers to waive their profit margin for patients receiving certain benefits — making their at-cost pricing effectively the wholesale price. This applies only to their service. More broadly, GLP-1 treatment remains expensive and out of reach for many people who could clinically benefit from it. The NHS rollout, while slow, is intended to address this for the highest-need patients.

Do prices change? How often should I check? ▾

Yes, frequently. Mounjaro prices rose significantly across all providers following Eli Lilly's September 2025 wholesale increase. Promo codes change — sometimes the same provider's code expires and reappears at a different value, as happened when EverydayMeds moved from FIRST40 (£40 off first order) to EDM25 (£25 off every order) in March 2026. cleardose* checks prices and codes weekly.